THE LIVER LECITHIN
نویسندگان
چکیده
منابع مشابه
Fatty Acids of Liver Lecithin
The phospholipids, along with cholesterol, are now recognized as essential elements of tissues, while the characteristic constituents of the phospholipids are the fatty acids. In any study of the metabolic activity of tissues the nature and proportions of the various fatty acids in the phospholipids therefore become important and have been the subject of increasing interest and speculation. Bec...
متن کاملDirect desaturation of eicosatrienoyl lecithin to arachidonoyl lecithin by rat liver microsomes.
A microsomal enzyme system from rat liver was shown to catalyze desaturation, in presence of reduced pyridine nucleotides and oxygen, of 1-acyl-2-[14C]eicosatrienoyl-sn-glycero-3-phosphorylcholine to 1-acyl-2-[14C]arachidonoyl-sn-glycerophosphorylcholine. This desaturation was linear with time and proportional to microsomal protein concentration, and proceeded with no significant breakdown of t...
متن کاملLecithin Synthesis, Intracellular Transport, and Secretion in Rat Liver
Injection of choline-(3)H into choline-deficient rats resulted in an enhanced incorporation of the label into liver lecithin, as compared to the incorporation of label into liver lecithin of normal rats. The results obtained with the use of different lecithin precursors indicate that in the intact liver cell, both in vivo and in vitro, exchange of choline with phosphatidyl-choline is not signif...
متن کاملLecithin-cholesterol acyltransferase and the lipoprotein abnormalities of parenchymal liver disease.
1. Detailed studies have been made of the plasma lipoprotein abnormalities in parenchymal liver disease to test the hypothesis that the abnormalities would correlate with plasma lecithin-cholesterol acyltransferase (LCAT) activity. 2. When LCAT was high, very-low-density-lipoproteins (VLDL) were normal in composition and had a normal pre-beta electrophoretic mobility. When LCAT was low, VLDL co...
متن کاملThe enzymatic formation of sphingomyelin from ceramide and lecithin in mouse liver.
The conversion of W-labeled fatty acylsphingosine and phosphatidyl[14C]choline to sphingomyelin could be demonstrated in lyophilized microsomes from mouse liver. Radioactive CDP-choline did not act as a choline donor. No cofactors were needed, although CDP-choline and P-choline exerted some stimulatory action. The unnatural ceramide, acetyl threo-sphingosine, could be converted to the correspon...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1921
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)86055-0